This journal issue of Bank Street College of Education’s Occasional Paper Series brings together Indigenous educators and researchers to demonstrate how Indigenous teaching and learning take form across contexts. Through eight articles, this issue focuses on how Indigenous knowledge systems, values, and ways of being are understood and enacted within socio-ecological systems grounded in reciprocal kin relations. The editors note that for Indigenous peoples, teaching, learning, living, and being in relation with human and more-than-human beings are central to Indigenous knowledge systems.